Dihydrotanshinone I

Dihydrotanshinone I is a compound extracted from the plantSalvie miltorrhiza Bunge. It is used as a gram positive antibacterial and anti-cancer compound. In bothin vivoandin vitroresearch, dihydrotanshinone I generated reactive oxygen species which trigger apoptosis in bacteria and cancer cells.Dihydrotanshinone I triggers apoptosis by directly damaging DNA and preventing further replication or by activating p38 mitogen-activated protein kinases (p38 MAPK) . This class of protein kinase engages apoptosis by activating caspases which are proteases that induce cell death. Dihydrotanshinone I has also been shown to inhibit cell growth past the G1 stage and prevent blood vessel formation by inhibiting hypoxia-inducible factor (HIF-1) activity.Product SpecificationsDihydrotanshinone ITanshinone I, dihydroFormula: C18H14O3MW: 278.30 g/mol