Camptothecin sodium

Camptothecin sodium is sodium salt of an alkaloid compound camptothecin, which is used for cancer research. Camptothecin is produced from endosymbioticAscomycota (Phycomycete) fungi present in the treeCamptotheca acuminataor the plantMappia foetida.Camptothecin sodium is a topoisomerase I inhibitor in DNA synthesis. It has been shown to bind and stabilize a topoisomerase I-DNA complexin vitro, preventing the enzyme from reannealing DNA strands. This inhibition specifically effects the S-phase of cell development and ultimately results in apoptosis due to damaged DNA.Product SpecificationsCamptothecin sodiumCamptothecin sodium saltSodium camptothecinFormula: C20H17N2NaO5MW: 388.35 g/mol