Bleomycin A5 hydrochloride

Bleomycin A5 hydrochloride is a compound part of the glycopeptide antibiotic family. It is currently used in oncology research for its strong stimulatory and inhibitory effects. Bleomycin A5 greatly reduces telomerase activity, hindering the proliferation of malignant cells. It has also been shown to inducein vivofibrosis and inflammation by generating peroxynitrites, a strong oxidizing agent.Bleomycin A5 stimulates downstream apoptosis by increasing cysteine-aspartic acid protease-3 (caspase-3) activity, tumor protein 53 (p53) production and transforming growth factor beta 1 (TGF-beta 1) formation. These proteins induce apoptosis directly or indirectly by halting cell growth.Product SpecificationsBleomycin A5 hydrochloridePingyangmycin1-Bleomycinoic acid hydrochlorideFormula: C57H89N19O21S2MW: 1477.02 g/mol