Spectinomycin Dihydrochloride Pentahydrate, USP Grade

Spectinomycin is an aminocyclitol antibiotic isolated fromStreptomyces spectabilis. It is effective against gram-positive and gram-negative bacteria, but most commonly used againstGonococcusspecies. It has also been used to monitor cell fate during leaf development and as a selection marker in plants to display successful transformation of theSpcrgene.Spectinomycin functions by binding the 30s ribosomal subunit, inhibiting tRNA translation and protein synthesis. Resistance to this antibiotic is conferred through theaadAgene and mutatedrpsEgene.Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic (s) to prescribe for various infections.TESTED AGAINST BOTH SENSITIVE AND RESISTANT CELLS.Product Specifications:Spectinomycin Dihydrochloride PentahydrateFormula: C14H24N2O7· 2HCl · 5H2OMW: 495.35 g/mol