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Axin2 Rabbit mAb

This is a Axin2 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin .Down-regulates beta-catenin.

Synonyms

Axil; Axin like protein; Axin2; Axis inhibition protein 2; Conductin

Swiss Prot

Q9Y2T1

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Axin2

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, IHC, ICC/IF

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

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