CDK7 Rabbit mAb

This is a CDK7 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

CDK-activating kinase (CAK) is a complex of CDK7 and cyclin H. The complex is involved in cell cycle regulation by phosphorylating an activating residue in the T-loop domain of cdks. Regulation of CAK activity is mediated by T-loop phosphorylation and by association with MAT1, both of which enhance its kinase activity toward the CTD of RNA polymerase II and other substrates such as p53.

Synonyms

Cyclin-dependent kinase 7; p39 Mo15; CDK-activating kinase 1; Cell division protein kinase 7; CDK7; CAK; CAK1; CDKN7; MO15; STK1

Swiss Prot

P50613

Reactivity

Human

Immunogen

A synthesized peptide derived from human CDK7

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:1000-1:2000

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

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