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Integrin alpha 2 Rabbit mAb

This is a Integrin alpha 2 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.

Synonyms

BR; CD 49b; CD49 antigen like family member B; Collagen receptor; GPIa; HPA5; ITGA2; Platelet glycoprotein GPIa; VLA 2 alpha chain

Swiss Prot

P17301

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Integrin alpha 2

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, IHC, ICC/IF, IP, FC

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:1000-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:100, FC 1:100

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

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