BTK Rabbit mAb
This is a BTK Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Btk plays an important role in B lymphocyte development, differentiation and signaling. Activation of B cells by various ligands is accompanied by Btk membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane-localized Btk is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223.
Synonyms
AGMX1; Tyrosine-protein kinase BTK; BTK; Agammaglobulinemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase; ATK; BPK
Swiss Prot
Q06187
Reactivity
Human
Immunogen
A synthesized peptide derived from human BTK
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IP
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:1000, IP1:20
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
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