TCF7L2 Rabbit mAb
This is a TCF7L2 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1.
Synonyms
TCF7L2; HMG box transcription factor 4; HTCF-4; T-cell factor-4 variant X2; T-cell factor 4; Transcription factor 7-like 2; TCF-4
Swiss Prot
Q9NQB0
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human TCF7L2
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, IP, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:5000-1:20000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:50, FC 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6330485-01 0.2 mL
PAFAH1B2, ID (PAFAH1B2, PAFAHB, Platelet-activating factor acetylhydrolase IB subunit beta, PAF acetylhydrolase 30kD subunit, PAF-AH subunit beta) (Biotin)
Ask
View Details 
MBS6330485-02 5x 0.2 mL
PAFAH1B2, ID (PAFAH1B2, PAFAHB, Platelet-activating factor acetylhydrolase IB subunit beta, PAF acetylhydrolase 30kD subunit, PAF-AH subunit beta) (Biotin)
Ask
View Details