ERR alpha Rabbit mAb
This is a ERR alpha Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Estrogen-related receptor alpha (ERRα/NR3B1) is an orphan nuclear receptor that controls transcription of genes involved in fatty acid oxidation, glucose metabolism, and mitochondrial biogenesis. The receptor protein contains a non-conserved amino terminal domain (NTD), a central zinc finger DNA binding domain, and a ligand-binding domain. The carboxy-terminal AF2 helix motif of ERRα contains binding sites for nuclear receptor coactivators PGC-1α and PGC-1β. Research studies demonstrate that ERRα transcriptional activity is regulated through phosphorylation and sumoylation within the NTD.
Synonyms
ESRRA; ERRa; ERR1; HERR1; NR3B1; Steroid hormone receptor ERR1; ERR-alpha; ERRalpha; ESRL1; Estrogen receptor-like 1; Estrogen-related receptor alpha
Swiss Prot
P11474
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human ERR alpha
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IP, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:1000-1:2000, IP 1:50, FC 1:20
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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