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FGFR1 Rabbit mAb

This is a FGFR1 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through cell surface receptor tyrosine kinases. Each receptor contains an extracellular ligand binding domain, a transmembrane domain, and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. Seven tyrosine residues in the cytoplasmic tail of FGFR1 can be phosphorylated: Tyr463, 583, 585, 653, 654, 730, and 766.

Synonyms

BFGFR; CD331; CEK; FGFBR; FLG; FLJ99988; FLT2; HBGFR; KAL2; N-SAM; OGD; FGF Receptor 1

Swiss Prot

P11362

Reactivity

Human

Immunogen

A synthesized peptide derived from human FGFR1

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, ICC/IF

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:500-1:1000, ICC/IF 1:50-1:200

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

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