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GRK2 Rabbit mAb

This is a GRK2 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

GRK2 kinase activity and cellular localization are tightly regulated by interactions with activated receptors, G-beta and G-gamma subunits, adaptor proteins, phospholipids, caveolin and calmodulin, as well as by phosphorylation. PKC phosphorylation enhances GRK2 activity by promoting its membrane localization and by abolishing the inhibitory association of calmodulin.

Synonyms

GRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1

Swiss Prot

P25098

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human GRK2

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, IHC

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

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