TPH1 Rabbit mAb

This is a TPH1 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the biosynthesis of serotonin by converting tryptophan to 5-hydroxy-L-tryptophan. Two isoforms of TPH exist: TPH-1 is mainly expressed in the periphery, whereas the expression of TPH-2 is restricted to neuronal cells and the central nervous system. Most of the serotonin found throughout the body is synthesized by TPH-1 in enterochromaffin cells of the gastrointestinal tract. Targeted disruption of the tph1 gene results in low levels of circulating and tissue serotonin.

Synonyms

TPH1; MGC119994; TPRH; TRPH; Tryptophan 5-hydroxylase 1; Tryptophan Hydroxylase

Swiss Prot

P17752

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human TPH1

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, IHC, IP

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:500-1:2000, IHC 1:50-1:200, IP 1:50

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

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