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Dnmt3a Rabbit mAb

This is a Dnmt3a Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development. Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2 and DNMT3. DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication.

Synonyms

DNMT3A2; M.HsaIIIA; Dnmt3a; MCMT; DNA methyltransferase 3a

Swiss Prot

Q9Y6K1

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Dnmt3a

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, IHC, ICC/IF, FC

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:500-1:2000, IHC 1:1000-1:2000, ICC/IF 1:100-1:500, FC 1:50

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Curated Selection

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