Dnmt3a Rabbit mAb
This is a Dnmt3a Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development. Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2 and DNMT3. DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication.
Synonyms
DNMT3A2; M.HsaIIIA; Dnmt3a; MCMT; DNA methyltransferase 3a
Swiss Prot
Q9Y6K1
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Dnmt3a
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IHC 1:1000-1:2000, ICC/IF 1:100-1:500, FC 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
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