M6PR Rabbit mAb
This is a M6PR Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Synonyms
IGF2R; CI Man-6-P receptor; CI-MPR; M6PR; MPR 300; Insulin-like growth factor 2 receptor; M6P/IGF2R; CD222
Swiss Prot
P11717
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human M6PR
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, IP, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:5000-1:20000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:30, FC 1:100
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
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