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NGFR Rabbit mAb

This is a NGFR Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

NGFR Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Homodimer; disulfide-linked. Interacts with p75NTR- associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. Interacts with KIDINS220 and NTRK1.

Synonyms

Gp80-LNGFR; NGF receptor; p75 ICD; CD271; NGFR; TNFRSF16

Swiss Prot

P08138

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human p75 NGF Receptor

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, IHC, ICC/IF, IP

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:10000-1:20000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:50

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

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