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Rad51 Rabbit mAb

This is a Rad51 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Rad51 is a recombinase that is essential for homologous recombination and double-strand break repair. It binds to single and double-stranded DNA, and has DNA-dependent ATPase activity. Rad51 unwinds duplex DNA and forms helical nucleoprotein filaments in a manner that is controlled through the action of DNA helicases that counteract nucleofilament formation. Rad51 interacts with BRCA1 and BRCA2, and also plays a role in p53-mediated signalling. Interaction of Rad51 with Chk1 kinase may occur in response to Chk1 phosphorylation.

Synonyms

RAD51; BRCC5; MRMV2; RECA; DNA repair protein rhp51; RAD51; BRCC5; MRMV2; RECA; DNA repair protein rhp51

Swiss Prot

Q06609

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Rad51

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, FC, IP

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:500-1:2000, IP 1:50, FC 1:50

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

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