CDC7 Rabbit mAb
This is a CDC7 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
DNA replication in eukaryotic cells is dependent on the phosphorylation of the pre-replicative complex (preRC) at the origin of replication. Two complexes of proteins mediate this event, the cyclin dependent kinase (CDK) complex, and the Cdc7 kinase-ASK complex. Human Cdc7 kinase consists of 574 amino acids with a molecular weight of 55 kDa. The activity of Cdc7 kinase oscillates during cell cycle. The major targets of Cdc7 kinase are proteins that belong to the MCM complex (mini chromosome maintenance proteins) .
Synonyms
Cell division cycle 7-related protein kinase; EC 2.7.11.1; CDC7-related kinase; HsCdc7; huCdc7; CDC7; CDC7L1; Hsk1 ; CDC7 kinase
Swiss Prot
O00311
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human CDC7
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:1000-1:2000, FC 1:100
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
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