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MCM2 Rabbit mAb

This is a MCM2 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The minichromosome maintenance (MCM) 2-7 proteins are a family of six related proteins required for the initiation and elongation of DNA replication. MCM2-7 bind together to form the heterohexameric MCM complex that is thought to act as a replicative helicase at the DNA replication fork. This complex is also a key component of the pre-replication complex (pre-RC) . Cdc6 and CDT1 recruit the MCM complex to the origin recognition complex (ORC) during late mitosis/early G1 phase forming the pre-RC and licensing the DNA for replication.

Synonyms

BM28; CCNL1; cdc19; CDCL1; cell devision cycle-like 1; cyclin-like 1; D3S3194; MCM2; MCM2 minichromosome maintenance deficient 2; mitotin

Swiss Prot

P49736

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human MCM2

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, IHC, ICC/IF

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:1000-1:5000, IHC 1:50-1:200, ICC/IF 1:50-1:200

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

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