Vinculin Rabbit mAb
This is a Vinculin Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development. Three structural vinculin domains include an amino-terminal head, a short, flexible proline-rich region and a carboxy-terminal tail. In the inactive state, the head and tail domains of vinculin interact to form a closed confirmation. The open and active form of vinculin translocates to focal adhesions where it is thought to be involved in anchoring F-actin to the membrane and regulation of cell migration.
Synonyms
Vinculin; VCL; Metavinculin; MV
Swiss Prot
P18206
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Vinculin
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, ICC/IF, IP
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:10000-1:20000, ICC/IF 1:50-1:200, IP 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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