HMGB1 Rabbit mAb
This is a HMGB1 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription.
Synonyms
HMGB1; HMG3; HMG1; SBP 1; Amphoterin
Swiss Prot
P09429
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human HMGB1
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:1000-1:2000, IHC 1:50-1:100, ICC/IF 1:50-1:100, FC 1:30
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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