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WRN Rabbit mAb

This is a WRN Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Multifunctional enzyme that has both magnesium and ATP-dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang. Has no nuclease activity towards single-stranded DNA or blunt-ended double-stranded DNA. Binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and Holliday junctions.

Synonyms

Exonuclease WRN; RecQ3; RECQL2; RECQL3; Werner syndrome helicase; WRN

Swiss Prot

Q14191

Reactivity

Human

Immunogen

A synthesized peptide derived from human WRN

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:500-1:2000

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

200kDa

Host or Source

Rabbit

Isotype

IgG

Curated Selection

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