RYK Rabbit mAb
This is a RYK Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
Synonyms
ERK 3; JTK5; JTK5A; Ryk; RYK1; Vik
Swiss Prot
P34925
Reactivity
Human
Immunogen
A synthesized peptide derived from human RYK
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, IP, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:1000-1:5000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:50, FC 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
72kDa
Host or Source
Rabbit
Isotype
IgG
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