TRIM25 Rabbit mAb
This is a TRIM25 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection.
Synonyms
EFP; RNF147; TRI25; TRIM 25; Trim25; Z147; ZNF147
Swiss Prot
Q14258
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human TRIM25
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, IP, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:1000-1:5000, IHC 1:50-1:200, ICC/IF 1:100-1:500, IP 1:50, FC 1:60
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
71kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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