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LSD2 / AOF1 Rabbit mAb

This is a LSD2 / AOF1 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.

Synonyms

AOF1; KDM1B; LSD2; Lysine-specific histone demethylase 1B; Lysine-specific histone demethylase 2

Swiss Prot

Q8NB78

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human LSD2 / AOF1

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, ICC/IF, IP, FC

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:500-1:2000, ICC/IF 1:50-1:200, IP 1:60, FC 1:50

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

92kDa

Host or Source

Rabbit

Isotype

IgG

Curated Selection

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