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Menin Rabbit mAb

This is a Menin Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL) -containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation. Menin functions to suppress proliferation of pancreatic islet cells, at least in part through MLL-mediated activation of the p18INK4c (p18) and p27CIP/KIP (p27) cyclin-dependent kinase inhibitor genes.

Synonyms

MEA1; Men1; Menin; Multiple Endocrine Adenomatosis 1; Multiple Endocrine Neoplasia 1; SCG2; Suppressor Candidate Gene 2; Wermer syndrome; ZES

Swiss Prot

O00255

Reactivity

Human

Immunogen

A synthesized peptide derived from human Menin

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, IHC, ICC/IF, IP

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:1000-1:5000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:50

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

68kDa

Host or Source

Rabbit

Isotype

IgG

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