Granzyme B Rabbit mAb
This is a Granzyme B Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Synonyms
Granzyme B; Cathepsin G-like 1; CTSGL1; Lymphocyte protease; Fragmentin-2; Granzyme-2; Human lymphocyte protein; SECT; GZMB; CGL1; CSPB; CTLA1; GRB
Swiss Prot
P10144
Reactivity
Human
Immunogen
A synthesized peptide derived from human Granzyme B
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
IHC, ICC/IF, IP
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:50
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
38kDa
Host or Source
Rabbit
Isotype
IgG
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