AFP Rabbit mAb
This is a AFP Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the mammalian fetal liver, yolk sac, and GI tract. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and β-catenin are associated with aberrant expression of AFP. Research studies have shown that elevated serum AFP levels are predictive of hepatocellular carcinoma .
Synonyms
Alpha fetoglobulin; Alpha fetoprotein precursor; FETA; HPAFP
Swiss Prot
P02771
Reactivity
Human
Immunogen
A synthesized peptide derived from human AFP
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, IP, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:50, FC 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
68kDa
Host or Source
Rabbit
Isotype
IgG
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