Caspase-7 Rabbit mAb
This is a Caspase-7 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Caspase-7 (CMH-1, Mch3, ICE-LAP3) has been identified as a major contributor to the execution of apoptosis. Caspase-7 is an effector caspase (along with caspase-2 and -3), meaning that it cleaves essential cellular machinery rather than activating other caspases. Caspase-7 is cleaved by many enzymes, including caspases-3, -6, -8, -9 and granzyme B. Once activated, caspase-7 cleaves many of the same substrates as caspase-3, including poly (ADP-ribose) polymerase, or PARP.
Synonyms
CMH-1; ICE-LAP3; MCH3; CASP7; Caspase-7; Caspase7
Swiss Prot
P97864
Reactivity
Mouse, Rat
Immunogen
A synthesized peptide derived from human Caspase-7
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, IP
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:1000, IHC 1:50-1:200, IP 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
34kDa
Host or Source
Rabbit
Isotype
IgG
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