P21 Rabbit mAb
This is a p21 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression. It functions in stoichiometric relationships forming heterotrimeric complexes with cyclins and cyclin-dependent kinases. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1/S. However, p21 may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D.
Synonyms
CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1
Swiss Prot
P38936
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human p21
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, ICC/IF
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, ICC/IF 1:50-1:200
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
21kDa
Host or Source
Rabbit
Isotype
IgG
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