C-Maf Rabbit mAb
This is a c-Maf Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.
Synonyms
Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene; c-MAF; c-maf proto-oncogene; cMaf; MAF; MGC71685; Proto-oncogene c-Maf
Swiss Prot
O75444
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human c-Maf
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
IHC 1:50-1:200
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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