Rad21 Rabbit mAb
This is a Rad21 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Rad21 is one of the major cohesin subunits that holds sister chromatids together until anaphase, when proteolytic cleavage by separase, a caspaselike enzyme, allows chromosomal separation. Rad21 interacts with Rec8 to form a cohesin complex that functions in sister chromatid alignment. Rad21 is also involved in the repair of double-strand breaks in DNA and is essential for mitotic growth. Rad21 undergoes a C-terminal cleavage induced by diverse stimuli right before apoptosis.
Synonyms
HHR21; Nuclear matrix protein 1; NXP-1; SCC1 homolog; HR21; KIAA0078; NXP1; Rad21
Swiss Prot
O60216
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Rad21
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:1000, FC 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
72,128kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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