MDM2 (Phospho-Ser166) Rabbit mAb
This is a MDM2 (Phospho-Ser166) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
Synonyms
ACTFS; Hdm2; HDMX; MDM2; MDM2BP; MTBP
Swiss Prot
Q00987
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-MDM2 (S166)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
100kDa
Host or Source
Rabbit
Isotype
IgG
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