Rad17 (Phospho-Ser656) Rabbit mAb
This is a Rad17 (Phospho-Ser656) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9-HUS1 complex onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
Synonyms
CCYC; hRad17; R24L; RAD17; Rad24
Swiss Prot
O75943
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-Rad17 (S656)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
85kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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