Chk2 (Phospho-Thr68) Rabbit mAb
This is a Chk2 (Phospho-Thr68) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
Synonyms
CHEK2; CHK2; Cds1; Chk2; EC 2.7.11.1; RAD53; kinase Chk2
Swiss Prot
O96017
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-Chk2 (T68)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IP
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IP 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
65kDa
Host or Source
Rabbit
Isotype
IgG
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