IKB alpha (Phospho-Ser36) Rabbit mAb
This is a IKB alpha (Phospho-Ser36) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Synonyms
I kappa B alpha; IkappaBalpha; IkB-alpha; IKBA; IKBalpha; MAD3; NF kappa B inhibitor alpha; NFKBI; NFKBIA
Swiss Prot
P25963
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human Phospho-IKB alpha (S36)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, FC 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
39kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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