ERK1/2 (Phospho-Thr202/Thr185) Rabbit mAb
This is a ERK1/2 (Phospho-Thr202/Thr185) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Synonyms
MAPK3; MK03; MNK1; p44-ERK1; P44-ER; ERK-1; ERK1; ERT2; kinase ERK1; MAP kinase 1; MAPK 1
Swiss Prot
P27361
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Phospho-ERK1 (T202) + ERK2 (T185)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, IP
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:1000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:40
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
42,44kDa
Host or Source
Rabbit
Isotype
IgG
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