MLKL (Phospho-Ser358) Rabbit mAb
This is a MLKL (Phospho-Ser358) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Synonyms
HMLKL; Mlkl
Swiss Prot
Q8NB16
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-MLKL (S358)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
54kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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