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Tau (Phospho-Ser324) Rabbit mAb

This is a Tau (Phospho-Ser324) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Tau is a heterogeneous microtubule-associated protein that promotes and stabilizes microtubule assembly, especially in axons. Six isoforms with different amino-terminal inserts and different numbers of tandem repeats near the carboxy-terminus have been identified, and tau is hyperphosphorylated at approximately 25 sites by ERK, GSK-3 and CDK5. Phosphorylation decreases the ability of tau to bind to microtubules.

Synonyms

MAPT; Microtubule-associated protein tau; MTBT1; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau

Swiss Prot

P10636

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Tau

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, ICC/IF, IP

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:1000-1:5000, ICC/IF 1:50-1:200, IP 1:50

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

79kDa

Host or Source

Rabbit

Isotype

IgG

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