Histone H2A.X (Phospho-Ser139) Rabbit mAb
This is a Histone H2A.X (Phospho-Ser139) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
Synonyms
H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X
Swiss Prot
P16104
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Phospho-Histone H2A.X (S139)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, IP
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:5000-1:10000, IHC 1:50-1:200, ICC 1:50-1:200, IP 1:30
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
15kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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