MTOR (Phospho-Ser2448) Rabbit mAb
This is a mTOR (Phospho-Ser2448) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
Synonyms
FRAP; FRAP1; FRAP2; RAFT1; Rapamycin target protein; kinase mTOR
Swiss Prot
P42345
Reactivity
Human, Mouse, Rat, Pig
Immunogen
A synthesized peptide derived from human Phospho-mTOR (S2448)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
289kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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