Akt (Phospho-Ser473) Rabbit mAb
This is a Akt (Phospho-Ser473) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
An AGC kinase that plays a critical role in controlling the balance between survival and AP0ptosis. Phosphorylated and activated by PDK1 in the PI3 kinase pathway. Mediates survival signals downstream of PI3 kinase and several growth factor receptors by phosphorylating AP0pototic proteins. First found in a mouse transforming retrovirus.
Synonyms
AKT; AKT1 kinase; C-AKT; PKB; PKB-alpha; Protein kinase B; RAC; RAC-PK-alpha
Swiss Prot
P31749
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Phospho-Akt (Ser473)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:100-1:500
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
60kDa
Host or Source
Rabbit
Isotype
IgG
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