GSK3ɑ/β (Phospho-Tyr216/Tyr279) Rabbit mAb
This is a GSK3ɑ/β (Phospho-Tyr216/Tyr279) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.
Synonyms
Glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK3A
Swiss Prot
P49840
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Phospho-GSK3 (alpha + beta) (Y216 + Y279)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, IP
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
51kDa/46kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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