Cdc6 (Phospho-Ser54) Rabbit mAb
This is a Cdc6 (Phospho-Ser54) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.Cdc6 has recently been shown to play an important role in the intra-S-phase p21 Waf1/Cip1-dependent DNA damage response. Both cdc6 and CDT1 are degraded by the ubiquitin proteasome pathway in response to DNA damage associated with re-replication.
Synonyms
CDC6; CDC18L; CDC6-related protein; Cdc18-related protein; HsCDC6; HsCDC18; p62 (cdc6)
Swiss Prot
Q99741
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-Cdc6 (S54)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, ICC/IF
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:1000, ICC/IF 1:50-1:200
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
63kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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