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BTK (Phospho-Tyr551) Rabbit mAb

This is a BTK (Phospho-Tyr551) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Bruton's tyrosine kinase (Btk) is a member of the Btk/Tec family of cytoplasmic tyrosine kinases. Like other Btk family members, it contains a pleckstrin homology (PH) domain and Src homology SH3 and SH2 domains. Btk plays an important role in B cell development. Activation of B cells by various ligands is accompanied by Btk membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate.

Synonyms

BTK; AGMX1; AT; ATK; XLA; PSCTK1; B-cell progenitor kinase; BPK; Bruton tyrosine kinase; Tyrosine-protein kinase BTK; IMD1

Swiss Prot

Q06187

Reactivity

Human

Immunogen

A synthesized peptide derived from human Phospho-BTK (Y551)

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, ICC/IF

Purification Method

Affinity purification

Assay Type

Antibody

Dilution

WB 1:500-1:2000, ICC/IF 1:50-1:200

Buffer

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

74kDa

Host or Source

Rabbit

Isotype

IgG

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