Chk1 (Phospho-Ser296) Rabbit mAb
This is a Chk1 (Phospho-Ser296) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Chk1 kinase acts downstream of ATM/ATR kinase and plays an important role in DNA damage checkpoint control, embryonic development, and tumor suppression. Activation of Chk1 involves phosphorylation at Ser317 and Ser345 by ATM/ATR, followed by autophosphorylation of Ser296. Activation occurs in response to blocked DNA replication and certain forms of genotoxic stress.
Synonyms
Checkpoint; S. pombe; homolog of;1; CHEK1; CHK1; CHK1 checkpoint homolog (S. pombe) ; Serine/threonine-protein kinase Chk1
Swiss Prot
O14757
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-Chk1 (S296)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
54kDa
Host or Source
Rabbit
Isotype
IgG
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