RPA2 (Phospho-Thr21) Rabbit mAb
This is a RPA2 (Phospho-Thr21) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation.
Synonyms
REPA2; RF-A; RP-A; RPA2; RPA32; replication factor-A protein 2; replication protein A 32 kDa subunit; replication protein A2
Swiss Prot
P15927
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Phospho-RPA2 (T21)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IP
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:5000-1:10000, IP 1:20
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
32kDa
Host or Source
Rabbit
Isotype
IgG
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