ATF2 (Phospho-Thr71) Rabbit mAb
This is a ATF2 (Phospho-Thr71) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines, and UV irradiation, stimulate the transcriptional activity of ATF-2. Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71.
Synonyms
ATF2; Activating 2; CREB2; CREBP1; Cyclic-AMP-dependent ATF-2; HB16; MXBP protein; cAMP response element binding protein CRE-BP1
Swiss Prot
P15336
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-ATF2 (T71)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, ICC/IF, IP
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, ICC/IF 1:50-1:200, IP 1:30
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
70kDa
Host or Source
Rabbit
Isotype
IgG
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