IRE1 (Phospho-Ser724) Rabbit mAb
This is a IRE1 (Phospho-Ser724) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Synonyms
ERN1; ER to nucleus signalling 1; Inositol-requiring enzyme 1; Inositol-requiring protein 1; Ire1-alpha; IRE1a; HIRE1p; IRE1; Inositol-requiring 1; IRE1P
Swiss Prot
O75460
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-IRE1 (S724)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
110kDa
Host or Source
Rabbit
Isotype
IgG
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