IKB alpha (Phospho-Ser32) Rabbit mAb
This is a IKB alpha (Phospho-Ser32) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Activation occurs via phosphorylation of IκBα at Ser32 and Ser36 followed by proteasome-mediated degradation that results in the release and nuclear translocation of active NF-κB. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines. Kinases that phosphorylate IκB at these activating sites have been identified.
Synonyms
I-kappa-B-alpha; IKBA; IkappaBalpha; MAD3; NFKBI; NFKBIA; RL/IF-1
Swiss Prot
P25963
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-IKB alpha (S32)
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IP
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IP 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
39kDa
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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